2022-11-01-世界卫生组织-Multi-country_outbreak_of_monkeypox,_External_situation_report_9_-_2_November_2022_15页_641kb
报告摘要
Monkeypox Multi-Country Outbreak Summary (WHO Report, November 2022)
Key Epidemiological Findings
- As of 31 October 2022, 77,264 laboratory-confirmed cases and 36 deaths were reported globally across 109 countries.
- Weekly new cases declined by 40.7% compared to the previous week, with declining trends observed since August 2022.
- Case concentration: The Americas and Europe accounted for 62% and 7.7% of global cases respectively, with the United States, Brazil, and Spain among the top contributors.
- Demographics: Cases disproportionately affected young men (96.9% of reported cases), with sexual transmission common (71.7% of events) and party settings as high-risk exposure sites.
- Mortality: 44.4% of deaths occurred in the Americas, with case severity varying, including complications like skin infections and lymphadenopathy.
WHO Risk Assessment and Recommendations
- Global risk: Moderate; regional risks include High in Europe and the Americas, Moderate in Africa and Eastern Mediterranean, Low in Western Pacific.
- Outbreak declared a PHEIC: The IHR Emergency Committee upheld the Public Health Emergency of International Concern status due to ongoing transmission, equity gaps, under-diagnosis, and stigma.
- Financing appeal: WHO requested $33.82 million (July 2022–June 2023) for vaccination, surveillance, diagnostics, and risk communication, prioritizing Africa, Southeast Asia, and Eastern Mediterranean.
- Operational guidelines: WHO issued planning tools for national responses, focusing on five core components (5Cs) and coordinated actions across public health pillars.
Outbreak Response Update
- Declining transmission rates observed since August, but months-long response needed due to persistent risks.
- High-risk populations targeted for stigma reduction and community engagement.
- WHO supported regions in financing, laboratory testing, surveillance, and clinical management.
- Clinical advice emphasizes symptomatic treatment and supportive care; antivirals under emergency protocols with ethical oversight.
Regional Highlights
- Americas: Highest burden of cases (50,716 cases, 16 deaths) and weekly new cases, with concentrated transmission among men in younger age groups.
- Other regions: Cases fewer in Europe and Asia but ongoing in Africa and Pacific areas; specific country data <21-day no-reports listed.
Further Notes & Resources
- Continuous monitoring and updates needed due to lag times in reporting and under-diagnosis.
- WHO guidelines and training modules provided here: [Links elided for brevity].
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