2025-05-07-世界卫生组织-Scalable_interventions_for_the_treatment_and_care_of_stimulants_use_disorders_12页_5mb

报告摘要

Background and Problem Statement

There is growing concern about global substance use, with stimulants (e.g., amphetamines, cocaine, ecstasy) being widely used internationally. In 2022, an estimated 292 million people used drugs, with stimulants ranking second. An estimated 30 million used synthetic stimulants, and there is a high demand for treatment due to variations across regions (e.g., 17-52% seeking help in different subregions). However, no approved pharmacological treatments exist, and psychosocial treatments are limited. This creates a significant treatment gap that must be addressed urgently to mitigate public health impacts.

#ScaleUp Initiative

The #ScaleUp Initiative is a collaborative effort by UNODC, WHO, and EUDA, launched in March 2024. It aims to scale up effective psychosocial treatments (contingency management, cognitive-behavioral therapy, family therapy, social support) and research on pharmacological options (e.g., prescription amphetamines). The initiative is based on previous work and expert discussions, emphasizing the need for scalable interventions to increase treatment engagement and retention globally.

Phases of Implementation

The initiative follows five phases:

Develop evidence-based protocols for psychosocial and pharmacological treatments, adapted for local settings, including low- and middle-income countries.
Conduct design and local preparation, including assessments, capacity building, and implementation studies.
Implement multi-country studies to test feasibility, effectiveness, and safety of interventions.
Monitor and evaluate the implementation process.
Disseminate results and develop recommendations for country-level follow-up and further research.

Expected Global Outcomes

Enhanced evidence and practical experience for scalable stimulant use disorder treatment in diverse regions.
Co-developed, human rights-based interventions supporting affected populations.
A global platform for information sharing and collaboration among countries, researchers, and agencies to promote effective and health-centered responses.