2025-02-12-世界卫生组织-Multi-country_outbreak_of_mpox,_External_situation_report_47_-_13_February_2025_24页_1mb

Mpox Multi-Country External Situation Report Summary

Report Details:

• Publication Date: 13 February 2025
• Covers Periods: 1 January 2022 to 31 December 2024; and 1 January 2024 to 2 February 2025

Objectives:

• Update on epidemiological situation and operational responses for mpox.

Key Findings:

1. Global Burden:

   • From 2022 to 2024, global mpox reported confirmed cases: 753,272, deaths: 124. In Africa, 21,113 cases and 70 deaths were reported.

2. Recent Trends (2024-2025):

   • Over 3,482 cases across Africa were reported in the past six weeks, highest in the Democratic Republic of the Congo (DRC) with 1,670 cases.

3. Outbreak Patterns:

   • Predominantly spreading in DRC, Burundi, and Uganda due to clade Ib monkeypox virus (MPXV).
   • Uganda has seen a surge with over a third of continent's cases in recent weeks.
   • DRC faces high transmission but challenges from violence in eastern regions.
   • Clade Ib MPXV also detected in non-African countries like UAE, Thailand, UK, China, etc., with no reported deaths elsewhere.

4. Operational Updates:

   • WHO is coordinating responses, enhancing surveillance, and distributing vaccines.
   • Vaccination efforts ongoing in at-risk groups, with updated guidelines.
   • Surveillance and clinical management tools being rolled out to control spread.

Strategic Recommendations:

• Continue monitoring, improve diagnostics, and strengthen community engagement.
• Address stigma and ensure equitable access to countermeasures.
• Preparedness for potential new outbreaks and variants.