2021-12-09-世界卫生组织-Inaugural_meeting_TAG-Arbovirus_8_-_10_December_2021_14页_492kb

Summary of the Inaugural Meeting of the Technical Advisory Group on Arboviruses

Core Content

The inaugural meeting of the Technical Advisory Group (TAG) on Arboviruses, held from 8-10 December 2021 as a virtual event, aimed to provide technical guidance to the World Health Organization (WHO) on the development and implementation of the Global Integrated Arbovirus Initiative (GLAI). The initiative is designed to address the growing global public health threat posed by arboviruses, particularly those transmitted by Aedes mosquitoes, through an integrated approach to prevention, preparedness, detection, and response.

Meeting Objectives

• To review and discuss the new version of the GLAI to move forward with endorsement and launch.
• To explore the relevance of other emerging and re-emerging arboviral diseases, including non-Aedes borne pathogens.
• To review the draft of the detection strategy for Aedes-borne arbovirus emergence or re-emergence.

Meeting Structure and Participants

• The meeting was conducted over three days, with plenary sessions and breakout discussions.
• Participants included newly appointed TAG members and the WHO-Arbovirus Secretariat.
• The Secretariat was composed of experts from various WHO departments, including WPE, WRE, UCN, and others.
• Dr. NG Lee Ching and Dr. Samuel Dadzie were appointed as Chair and Vice-Chair of the TAG-GLAI, respectively.

Main Discussion Topics and Priority Actions

GLAI Pillar 1: Monitor Risk and Anticipate

• Develop a global risk monitoring framework using an integrated approach.
• Forecast and model epidemic and pandemic scenarios with high-quality data and uncertainty estimates.
• Integrate local transmission dynamics and One Health parameters into models.
• Use a global dashboard to monitor transmission, outbreak risk, and disease burden.
• Update disease burden and economic impact assessments for all relevant arboviruses.

GLAI Pillar 2: Reduce Epidemic Risk

• Strengthen early detection methods and standardize case definitions.
• Expand decentralized testing and improve epidemiological investigation using risk maps.
• Improve outbreak response through logistical and clinical preparedness.
• Implement the EYE strategy to enhance yellow fever vaccination in high-risk areas.
• Develop an economic investment case to engage policy-makers.

GLAI Pillar 3: Strengthen Vector Control

• Enhance vector surveillance through expanded entomological training and collaboration with malaria programs.
• Standardize vector surveillance and develop guidance for its implementation.
• Validate vector control tools through both lab and field studies.
• Integrate vector and human data for targeted interventions.
• Promote ecological studies to understand vector dynamics and climate change impacts.

GLAI Pillar 4: Prevent and Prepare for Pandemics

• Enhance global coordination among stakeholders through mapping and synergy identification.
• Strengthen surveillance mechanisms for rapid response, using real-time data sharing.
• Build community engagement and resilience through trusted communication and awareness campaigns.
• Leverage traditional and global media for arbovirus awareness.

GLAI Pillar 5: Enhance Innovation and New Approaches

• Develop an integrated public health research agenda focusing on arbovirus transmission, disease severity, and One Health approaches.
• Support implementation research for multisectoral collaboration, including local government and health ministries.
• Use AI-based tools to improve diagnosis and differentiate arbovirus infections from other diseases.
• Investigate community knowledge, awareness, and perception using social science methods.
• Promote Communication for Behavioural Impact (COMBI) and other methods to sustain behavior change.

GLAI Pillar 6: Build a Coalition of Partners

• Develop a public health research agenda for Aedes-borne arboviruses.
• Support the development of innovative countermeasures, including vaccines, diagnostics, and vector control tools.
• Expand partnerships to include non-traditional stakeholders like the tourism industry and commercial interests.
• Leverage existing networks and collaborate with WHO Collaborating Centers to co-fund activities.

Non-Aedes Borne Arboviruses

• Dr. Erin Staples highlighted the need to include more non-Aedes borne arboviruses in future discussions.
• The lessons learned from focusing on Aedes-borne diseases will be used to expand the initiative to other arboviruses, especially in countries where these viruses are of higher public health priority.

Global Arbovirus Surveillance and Response Capacity Surveys

• Preliminary data from a global survey of Aedes (Stegomyia) borne arboviruses were presented.
• The data will help target programs and interventions, and will be validated by member states before broader publication.

Proposed Arbovirus Detection Toolkit

• A detection toolkit was introduced to support earlier identification of arbovirus emergence or re-emergence.
• The toolkit includes human and vector surveillance, sentinel sites, and laboratory testing options.
• Initial feedback from TAG members was collected, with further discussions planned.

Meeting Conclusion

• The meeting concluded with plans for updating the GLAI strategy document based on TAG feedback.
• Future meetings will be held to finalize the strategy and launch the initiative.

Key Takeaways

• The GLAI is a comprehensive, integrated approach to addressing arboviruses.
• Technical collaboration, stakeholder engagement, and multisectoral coordination are critical for success.
• Emphasis is placed on data quality, early detection, and innovative tools for diagnosis and response.
• Non-Aedes borne arboviruses will be integrated into the strategy moving forward.
• The detection toolkit and capacity surveys will guide future actions and resource allocation.

Appendix Summary

• Appendix 1: Lists the 18 members of the TAG-Arbovirus for the period 2021-2023.
• Appendix 2: Details the WHO TAG-Arbovirus Secretariat members.
• Appendix 3: Includes declaration of interest statements from members, highlighting no direct conflicts of interest.
• Appendix 4: Provides the meeting agenda, including dates, times, and sessions.
• Appendix 5: Includes a group photo of the meeting participants.