2015-06-08-世界卫生组织-INN_Proposed_List_113_107页_735kb

报告摘要

Proposed INN from WHO Drug Information, Vol. 29, No. 2, 2015, List 113

Overview

This list includes 41 proposed International Nonproprietary Names (INN) for innovative pharmaceutical substances. These names are subjects of formal review and potential recommendation by the World Health Organization (WHO). The proposed names cover a wide range of therapeutic classes, including:

Immunomodulators (e.g., acalabrutinibum, afasevikumabum)
Antineoplastics (e.g., altiratinibum, amonuromabum)
Vaccines and adjuvants (e.g., ciraparantagum)
Complex therapeutic agents (e.g., simvuvacumabum)
Recruitment inhibitors (e.g., repot-0001)
Glycoforms and other derivatives (e.g., nadorameranum)

Key Notes

Comments or formal objections can be submitted within 4 months from the publication date.
Some proposed names include conjugated forms (e.g., fusion proteins, PEGylated antibodies).
Three amendments were made to previous lists, affecting certain INN.

Examples of Proposed INN:

acalabrutinibum: Tyrosine kinase inhibitor.
afasevikumabum: Immunoglobulin used for immunomodulation.
altocilumabum: Monoclonal antibody for immunomodulation.
asemoesannam: mRNA vaccine encoding rabies virus glycoprotein.
avicumabum: Monoclonal antibody targeting complement system.

For a complete list, refer to the original publication and supplementary lists (List 107, List 111). The full details include chemical names, arbitrary actions, and descriptors.

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