2012-06-08-世界卫生组织-INN_Proposed_List_107_79页_674kb

List of Proposed INN for 2012 (List 107) - Medical Compounds

Proposed INN and Key Information:

1. Actoxumabum: Immune globulin anti-toxin A of Clostridium difficile.
2. Aladorianum: Anti-arrhythmic, 7-methoxy derivative.
3. Alirocumabum: Immune globulin anti-PCSK9.
4. Antithrombinum gamma: Gamma antithrombin, modified fucosyl.
5. Balugrastimum: Granulocyte colony-stimulating factor pegylated.
6. Birulipasum: Enzyme from Burkholderia.
7. Cobimetinibum: MEK inhibitor for cancer.
8. Crizanospasum: Crizanumab pegol for hemophilia.
9. Danirixinum: Interleukin-8 (IL-8) inhibitor.
10. Duligotumabum: Monoclonal antibody against CFD.

Additional Notes:

• Validity: Comments or objections due by October 31, 2012.
• Provisional Nature: These names are not permanently adopted until conclusions are reached.
• Review Process: The INN Programme ensures evaluation and modifications if needed.

Summary

This document lists proposed International Nonproprietary Names (INN) for pharmaceutical substances. Each entry includes the official name, its essence (e.g., therapeutic use), and CAS Registry Number or molecular formula for identification. These names are submitted to allow comments or objections within four months for adoption as global standards. Such INNs facilitate safety and avoid confusion in medical contexts.