2005-12-08-世界卫生组织-INN_Proposed_List_96_34页_258kb

报告摘要

INN List 96 Summary

This document outlines the Proposed International Nonproprietary Names (INN) for pharmaceutical substances listed in WHO Drug Information, Vol. 20, No. 4, 2006 (List 96), published on January 31, 2006, with a four-month comment and objection period ending May 31, 2007.

Key Points from the Summary

Purpose: The list includes 96 potential INN for new pharmaceutical substances under consideration by WHO. These are not recommendations and may change during review.
INN Proposed: Each entry includes the proposed INN, chemical name, action/indications, molecular formula, CAS registry number, and graphic formula (where applicable).
Procedures and Objectives:
- Any individual can submit comments or formal objections within the specified period.
- Formal objections must include details of the objector, their interest, and reasons.
- If objections persist, the substance's name may not be adopted as recommended.
- After review, the INN could be recommended, modified, swapped, or retained, following established guidelines.
General Principles for INN Naming:
- INNs should be distinctive, pronounceable, and not confusing with existing names.
- Prefer one-word names for acids and their salts.
- Avoid surplus letters or numbers; use f for ph, t for th, etc., for readability across languages.
- Common stems are used for pharmacologically related substances (e.g., -cillin for penicillins).
Amendments to Previous Lists: The document includes corrections to earlier lists (e.g., List 90, 91, 93, 95).
Full Details: The original list provides extensive technical information, including the chemical structure for some INNs. The detailed procedures in the annex cover proposal submissions, notifications, comments, and final recommendations by WHO.