2023-01-24-世界卫生组织-Weekly_epidemiological_update_on_COVID-19_-_25_January_2023_18页_1mb

Summary of the WHO Weekly Epidemiological Update (Edition 127, 25 January 2023)

Core Content

This report provides an overview of the global and regional trends in COVID-19 cases and deaths, SARS-CoV-2 variants, and hospitalizations and ICU admissions as of 22 January 2023.

Global Overview

• New cases: 1.9 million were reported in the week of 16–22 January 2023.
• New deaths: Over 12,000 were reported in the same week.
• 28-day trends: Cases decreased by 25%, while deaths increased by 13% compared to the previous 28 days.
• Cumulative cases: Over 664 million confirmed cases globally.
• Cumulative deaths: Over 6.7 million deaths globally.
• Underreporting concerns: Weekly and monthly trends may be underestimated due to reduced testing and reporting delays, especially around holidays.

Regional Trends

Key Variants and Trends

• Omicron variant: Dominates globally, accounting for 99.9% of all sequences reported in the past 30 days.
• BA.5 and its descendants remain the most prevalent variant.
• BA.2.75 and XBB are rising in prevalence.
• XBB.1.5:
  • Has been reported in 54 countries (excluding low coverage sequences).
  • Dominates in the United States (75.0% of sequences).
  • Shows a growth advantage over other Omicron lineages.
  • Preliminary studies suggest higher immune escape than previous Omicron variants, though this needs confirmation.
  • No early signals of increased severity have been observed, but case numbers are still low.

Hospitalizations and ICU Admissions

• Global hospitalizations (Week 2, 9–15 Jan 2023): 15,062 new cases reported.
• Global ICU admissions (Week 2): 880 new cases.
• Regional reporting:
  • Europe had the highest proportion of countries reporting hospitalizations (28%).
  • Eastern Mediterranean had the highest proportion of countries reporting ICU admissions (23%).
• Countries with increasing trends:
  • Ukraine: +50% increase in hospitalizations.
  • Belgium: +9% increase in hospitalizations.
  • Greece: +7% increase in hospitalizations.
  • Mexico: +73% increase in ICU admissions.
  • Ireland: +22% increase in ICU admissions.
  • Greece: +24% increase in ICU admissions.

China's Situation

• New cases (Week 16–22 Jan 2023): 142,066, down by 25% from the previous week.
• New deaths (Week 16–22 Jan 2023): 617, down by 23%.
• Fever clinic visits: Peaked at 2.867 million on 22 December 2022, declining to 63,000 by 23 January 2023.
• Hospitalizations: Reached a peak of 1.625 million on 5 January 2023, declining to 248,000 by 23 January.
• Severe cases: Peaked at 128,000 on 5 January, declining to 36,000 by 23 January.
• Hospital deaths: 72,596 were reported from 8 December 2022 to 19 January 2023, but not included in the global death count yet.
• Vaccination:
  • 3.488 billion doses administered.
  • 90.5% of the population has received the primary series.
  • 92% of those over 60 have received a booster dose.

Additional Information

• Data limitations: Trends may be inaccurate due to changes in testing strategies, reporting delays, and underreporting.
• Variant monitoring: WHO is tracking BA.5, BA.2.75, XBB, and BQ.1.
• Resources:
  • WHO Dashboard and Monthly Operational Update.
  • Genomic sequencing guide and vaccine data repository (VIEW-hub).
• Annex 1: Contains detailed data notes and regional updates.
• Annex 2: Summarizes China's update, including fever clinic visits, hospitalizations, and deaths, with no independent WHO analysis available.
• Annex 3: Explains WHO's process for assessing and classifying SARS-CoV-2 variants.

Key Points

• Global cases and deaths are decreasing in most regions, but some areas like the Eastern Mediterranean show increases.
• XBB.1.5 is a rising concern due to its immune escape potential and growth advantage.
• China's data is not fully integrated into the global report due to delayed reporting and hospital deaths.
• Hospitalization and ICU data is limited and subject to delays and underreporting, especially in some regions.
• Testing strategies and reporting practices vary by country, affecting data accuracy.