2025-05-13-世界经济论坛-针对性行动和资助亚洲对抗抗菌素耐药性的斗争（英）_52页_5mb

Summary of "Targeted Action and Financing the Fight Against Antimicrobial Resistance in Asia"

Key Findings

• AMR is a severe global health crisis projected to surpass cancer as the leading cause of death by 2050, with an estimated 10-15 million annual deaths.
• Economically, unmitigated AMR could reduce annual global GDP by 1.1%–3.8% by 2050.
• Asia bears a disproportionate burden, with AMR deaths projected to reach 4.4 million by 2050, accounting for over 50% of global deaths in 2021.
• Climate change exacerbates AMR by worsening sanitation, increasing antibiotic misuse, and enabling spread via waterways.
• The "One Health" approach is essential for effective AMR combat, integrating human, animal, and environmental health.

Regional Focus: Asia

• Healthcare Challenges: Many Asian countries lack sufficient healthcare infrastructure, WASH facilities, and skilled professionals.
• Agricultural Practices: Overuse of antibiotics in livestock farming contributes to AMR, particularly in South-East Asia.
• Demographics: Aging populations, especially in East Asia, increase vulnerability to AMR.
• Economic Impact: AMR could cost Asia’s GDP 0.8–1.0% annually by 2050.

Proposed Strategies

Three Sprints & One Marathon

1. Educate: Improve antimicrobial stewardship and public behavior through education.
2. Prevent: Strengthen health systems, diagnostics, WASH infrastructure, and surveillance.
3. Monitor: Enhance regional data sharing and surveillance to track AMR trends.
4. Treat (Marathon): Invest in R&D for novel therapeutics and vaccines, ensuring equitable access.

Recommendations

• Philanthropy, investors, and businesses must collaborate to fund AMR solutions.
• Government policies should incentivize antibiotic innovation, enforce stewardship, and promote sustainable farming practices.
• Cross-border partnerships are crucial for comprehensive AMR surveillance and response.

Call to Action

• URGENT funding is needed to bridge the R&D gap and scale sustainable solutions across the Asia-Pacific.
• Over USD 443 billion in annual productivity losses is projected by 2035 if AMR remains unaddressed.
• Coordinated efforts from all stakeholders—governments, private sector, and communities—are essential to prevent AMR from becoming a global catastrophe.