2022-07-05-世界卫生组织-Immunization_Republic_of_Moldova_2022_country_profile_17页_373kb

Summary of Moldova's Immunization Coverage Estimates (2021 Revision)

Overview

WHO and UNICEF joint estimates for immunization coverage in the Republic of Moldova, based on data up to 2021. These estimates address vaccines such as BCG, DTP, MCV, IPV, HepB, Hib, RCV, RotaC, and PcV3. The estimates rely on various data sources, including national reports, surveys, and administrative data, with a grade of confidence provided for reliability. Coverage levels show variability due to data quality, recent declines in numerators, and lack of recent surveys.

Key Findings and Trends

• Overall coverage for most vaccines was high during early years (e.g., between 90-99% in 2004-2011), but experienced a decline since 2019, with a 10-16% reduction in numerators (target population) and coverages ranging from 83-98%.
• Short-term fluctuations occurred, with some years showing minor drops or rises, often due to factors like vaccine stockouts (2016, 2018, 2020) or changes in survey methodologies.
• Confidence levels (GoC) varied: many estimates were supported by reported data and denominator recalculations, but some were challenged due to potential biases or insufficient supporting surveys, noted as GoC ~ or challenged.
• Recommendations from WHO and UNICEF emphasize the need for higher-quality data and national surveys to verify recent estimates.

Data and Methodology Issues

• Estimates are country-specific and not data-borrowed, with emphasis on empirical support but caution due to potential inaccuracies in numerator/denominator data.
• A period of declining target populations (since 2016) contributed to lower confidence in several estimates.
• No nationally representative household surveys conducted within the last five years, prompting calls for improved survey-based verification.
• Some estimates were rated with confidence grades indicating moderate support or challenges from localexperts, data sources, or biases.

Vaccines Covered

• BCG, DTP, MCV, IPV, HepB, Hib, RCV, RotaC, PcV3 highlights. Each had specific coverage trajectories, e.g., MCV1 stayed above 90% except recent years, while Hib3 showed mixed coverage.
• Overall, coverage peaked around 1999-2004, declined from 2013-2019, and saw cautious recovery in 2020-2021.

Conclusion

Immunization coverage in Moldova has faced reliability issues in recent data, with advice for stronger surveillance and surveys. The estimates should be used cautiously due to potential biases and data limitations.