2022-10-27-世界卫生组织-ACT-Accelerator_Transition_Plan_1_Oct_2022_to_31_Mar_2023_46页_1mb

报告摘要

Purpose: To outline how the ACT-Accelerator will operate for operating plan ending Oct 2022, focusing on transitioning support from emergency COVID-19 management to long-term control.
Objectives: Ensure sustained access to COVID-19 vaccines, diagnostics, and therapeutics for management, while maintaining readiness for potential surges.

Pandemic Status: COVID-19 requires long-term management; transitioning activities into routine health systems.
Key Focus Areas (Base Case):
1. Strengthen R&D: Continuously develop and ensure pipeline maturity for new/modified COVID tools (vaccines, tests, treatments).
2. Secure Access Arrangements: Finalize longer-term access mechanisms (procurement, distributed manufacturing, tech transfer).
3. Concentrate Delivery: Focus support on rollout of tools (especially boosters, therapeutics, tests) for priority populations and national targets, while maintaining surge capacity.

Focus: Support vaccine delivery for priority populations (high-risk groups, boosters) in AMC countries, transition towards programmatic integration into Immunization programs. Shift focus to variant-containing vaccines if needed.
Activities: Procurement support, coordination, deployment support via CoVDP; agile allocation process; assess/deliver Variant Containing Vaccines (VCVs) early; continue regulatory and prequalification work.

Focus: Shift from acute response to long-term management and surveillance. Prioritize scaling self-testing, sustaining genomic sequencing, and strengthening test-and-treat/treatment linkage.
Activities: Expand local manufacturing and tech transfers; support procurement/supply/delivery; scale affordable/accessible self-testing; maintain genomic surveillance capacity; support point-of-care testing (POCT); integrate diagnostics into routine surveillance.

Focus: Support rollout of oral antivirals for high-risk patients; work closely with Diagnostics on test-and-treat programs.
Activities: Procure/secure/supply therapeutic medicines (NAVs); maintenance of market shaping for accessible generics/originator licenses; coordinate oxygen needs through the Oxygen Taskforce until transition to a Global Oxygen Alliance.

Function: Provides cross-cutting support across pillars.
Focus: Transition coordination support to agencies; maintain readiness for surge capacity; continue support for essential health services, vaccination campaigns, and community mobilization in crisis contexts. Shift focus from emergency funding to supporting national plans and addressing essential service disruptions.

Consolidation: ACT-A Facilitation Council enters standby mode (meets only if surge needed). New ACT-A Tracking and Monitoring Task Force established.
Coordination: Hub supports Pillar meetings, coordination forums (Principals, Agency Leaders, CSO Platform), and reporting (Commitment Tracker). ACT-A Coordination Office now considered for future structure.

Gap: A $386 million funding gap was identified for the 6-month base case, mostly for support tasks already integrated into existing budgets or pipeline funds.
Approach: No new specific budget developed. ACT-A agencies use their regular resource mobilization (RM) processes; the new Tracking and Monitoring Task Force facilitates tracking and coordination. Coordination of ACT-A financing continues via the Commitment Tracker.

Base Case: Current epidemiological trend continues (ongoing, manageable outbreaks). Supports transition to long-term control.
Surge Scenarios (activated if needed): Plan for potentially more severe events, requiring rapid reactivation of full ACT-A capacity.

Knowledge Management: Maintain a platform to capture and share ACT-A lessons learned.
PPR Contribution: Embed ACT-A lessons into discussions on the future Pandemic Preparedness, Response architecture, particularly concerning equity, finance, and capacity building.

展开完整摘要