2003-08-07-世界卫生组织-Weekly_epidemiological_record,_2003,_vol._78,_32_full_issue_8页_418kb

The Fourth Meeting of the Steering Committee on Immunization Safety, held in Geneva in June 2003, focused on evaluating progress toward establishing comprehensive immunization safety systems. Key achievements include improved safety integrations, but challenges remain in least developed countries, economies in transition, and regulatory capacity. Recommendations emphasize cautious integration, ensuring auto-disable syringe use, enhancing adverse event surveillance, and strengthening collaboration with health ministries.

The meeting recommended maintaining visibility of immunization safety issues, increasing resources, and promoting communication strategies at all levels. Specific actions include better management of injection safety, supporting national regulatory authorities, and addressing health-care worker risks. Countries were urged to adopt best practices for vaccine storage, disposal, and monitoring.

The Global Advisory Committee on Vaccine Safety (GACVS) reviewed vaccine safety concerns, reaffirming recommendations for vaccines like yellow fever and thiomersal, while addressing issues with mumps, BCG, and smallpox vaccines. Findings indicate that no changes are needed to current policies, but ongoing surveillance is required for special risk groups, such as immunocompromised individuals.

Following the isolation of poliovirus MEF-1 in India in late 2002 involving acute flaccid paralysis cases, investigations were conducted to assess community circulation and vaccine sources. Alternative vaccine supplies were deployed pending further testing, and recommendations stress rigorous quality control to prevent future occurrences.