2012-03-08-世界卫生组织-INN_Recommended_List_67_52页_465kb

Recommended INN List 67 Summary

Introduction

This document from the World Health Organization (WHO) details the Recommended International Nonproprietary Names (INN) for pharmaceutical substances in List 67, published in WHO Drug Information, Vol. 26, No. 1, 2012. The selection follows specific procedures, and inclusion does not imply a recommendation for medical or pharmacological use. The lists are available on CD-ROM or the WHO website.

Key Details

• Year Published: 2012
• List Number: 67
• Number of Recommended Names: Includes names in Latin, English, French, and Spanish.
• Scope: Covers a variety of pharmaceutical substances, including small molecules, biologics, and antibodies.
• Amendments: Provides updates to previous lists (e.g., corrections for beraprost, olodaterol).
• General Principle: All INN recommendations are reviewed periodically, and users should consult the latest sources for accurate information.

Notable Substances from the List

The list includes complex molecules such as:

• Abexinostat: A histone deacetylase inhibitor with chemical structures.
• Blosozumab: A monoclonal antibody targeting sclerostin.
• Cabozantinib: A tyrosine kinase inhibitor.
• Others: Compounds like daratumumab ravtansine, lenomorelin, and many more are detailed.

Summary Notes

• The INN system aims to provide nonproprietary names for safe and standard use in medicine.
• This list emphasizes precision in nomenclature and includes structural data for clarity.
• Regular updates ensure INN remain current with scientific advancements.

For detailed names and structures, consult the source document and associated guidelines.