2012-01-20-世界卫生组织-Meningitis_Week_03,_16_-_22_January_2012_8页_909kb

Meningitis Weekly Bulletin Summary

I. Epidemiological Situation Week 03 (January 16-22, 2012)

• Total cases reported: 255 cases across West African countries.
• Total deaths: 27 deaths, overall case fatality rate (CFR) of 10.6%.
• Districts in alert or epidemic:
  • Benin: Tangieta district (attack rate: 8.2 per 100,000).
  • Côte d'Ivoire: Tangrela district (attack rate: 10.7 per 100,000; caused by NmW135).
• Laboratory findings: Most cases confirmed with PCR, LATEX, or Culture methods. Notable pathogens include NmW135 (Neisseria meningitidis serogroup W135) and Streptococcus pneumoniae (Spn) in some regions.

II. Synthesis of 2012 (Weeks 01–03)

• Total cases over three weeks: 630 cases.
• Overall CFR: approximately 9.7%.
• Epidemic alerts: 5 districts across different countries were in alert status.
• Comments: The epidemiological situation in countries like Sudan is calm, but it is encouraged to strengthen surveillance during the pre-epidemic season and share timely data for informed decision-making.

III. Laboratory Findings

• Reported pathogens:
  • Neisseria meningitidis was the primary pathogen identified.
  • Sub-serogroups included W135 and others.
  • Streptococcus pneumoniae and other less common pathogens accounted for a portion of cases.
• Lab results: Most cases confirmed via PCR and Culture methods, with some using LATEX tests.

IV. Additional Notes

• The report highlights the need to focus on Neisseria meningitidis serogroup W135 in districts that have introduced the MenAfriVacTM vaccine.
• Data is subject to change once verified and completed.