2016-03-04-世界卫生组织-Report_of_the_Workshop_on_Human_Biomonitoring_HBM_to_Support_Chemical_Risk_Assessment_16页_247kb

Workshop Overview

The WHO workshop on Human Biomonitoring (HBM) to support chemical risk assessment was held in Bangkok, Thailand, from November 17 to 19, 2016. It aimed to foster collaboration among participants from WHO's Chemical Risk Assessment Network and invited experts. Key goals included sharing knowledge on HBM activities, reviewing methodologies for resource-poor countries, identifying case studies, and formulating recommendations for broader application in chemical risk management.

Key Objectives

• Facilitate information exchange between network members and experts on HBM.
• Showcase tools and resources available to support HBM efforts.
• Evaluate existing HBM methodologies suitable for low-resource environments.
• Identify and disseminate HBM case studies from network members to build capacity.
• Develop conclusions and recommendations for the wider network.

Main Themes and Contributions

HBM Applications and Case Studies

• Presentations highlighted HBM uses in various regions, such as Spain's national HBM initiatives for environmental surveys and health declarations.
• Costa Rica discussed challenges in resource-poor settings, including pesticide exposures with issues like inadequate metabolite selection and neurotoxicity protocols.
• Canada detailed the evolution of HBM data in risk assessments, including tiered approaches for prioritizing substances and improving exposure pattern analysis.
• Israel and Thailand shared experiences on pesticide and POP exposures, emphasizing communication with policymakers and occupational health surveillance.
• India described institutional efforts in air pollution studies, noting practical barriers like analytical costs and equipment availability.
• The UNEP/WHO mercury biomonitoring project (involving multiple countries) stressed training and global data harmonization.

Round Table Discussions

• Developing countries shared experiences on building risk assessment capacity, focusing on local issues like mercury from artisanal mining, lead from batteries, and pesticide use.
• Challenges included fragmented responses to incidents, limited access to research findings, and workforce gaps in implementing surveillance.
• Case studies from Thailand and others underscored the need for separate community reference values and surrogate markers due to informal sector exposures.

Conclusions and Recommendations

HBM's scope has expanded beyond occupational health to include community and environmental assessments. Data quality and inter-comparability are critical for effective risk assessment. Key recommendations emphasize data sharing, standardized protocols, and capacity-building efforts, with a focus on improving reference values for non-occupational and public health contexts. The workshop stressed the need for continued international collaboration to address global chemical risks.